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Ethics Gradient's avatar

Writing a dominant assurance contract that the frontier labs can sign on to seems like a very "You Can Just Do Things" project.

Jeffrey Soreff's avatar

Many Thanks for your post!

"3.Tyler thinks AI can cure cancer and heart attacks but not aging?"

Curing heart attacks (cancer is questionable - really many diseases) but not aging is plausible. The heart is a _pump_. Implantable artificial hearts are a mechanical _engineering_ problem. A hard one, but partially solved even decades ago ( https://library.med.utah.edu/publishing/exhibition/utah-and-the-artificial-heart-impact-and-reflections-forty-years-later/ ).

Aging, on the other hand, is still a scientific _research_ problem. Now, _solving_ it would probably be the biggest improvement in the human condition ever, dwarfing the gains from e.g. somehow stopping every single war. Regrettably, it is an _exceedingly_ hard technical problem. We humans live for about 3 billion heartbeats. Other mammals typically live for about 1 billion heartbeats. What we would really need to test aging interventions is a small primate with a much faster metabolism than ours but which also lives for 3 billion heartbeats in a much shorter time. AFAIK, there is no such animal, so we are stuck without an animal model - and the efficacy feedback from human studies will necessarily take on the order of a lifetime. Validating biomarkers for aging has the same problem. Ruling out side effects from a candidate treatment has the same problem. The feedback loop is _slow_.

Re: "It is not obvious how policymakers would use this information. The usual default is that they go and make things worse."

Agreed.

Re: "[about AI] — so society and regulation could catch up"

I suspect that for almost any significant technology, that the time when policymakers would agree that regulation had caught up is ... never. I've heard claims that, in some senses, "society and regulation" has not fully adapted to ... the printing press. I've seen the US gradually transform for a "can do" society to a "mustn't do" society. I do not want to put AI on that same path. It is _really_ hard to ensure that a policymaker does no harm. Generally, as you said, "they go and make things worse". Personally, I prefer the risks of a competitive AI development environment to the risks of a policymaker-dominated environment.

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