13 Comments

SGTF might stop being a good proxy for Omicron, because we now have a subvariant of Omicron that doesn't manifest it.

https://github.com/cov-lineages/pango-designation/issues/361 says:

> The new sub-lineage (putative BA.2) does not carry the spike:69/70del deletion and will thus not be detectable by SGTF (S-gene target failure).

Expand full comment

Is there a reason for not including an IFR or some sort of mortality prediction? These other questions around transmissibility, immune escape, and policy are interesting but it feels like a lot of folks are sidestepping what would seem to be the most important question.

Expand full comment

Re Israel - it was already letting in citizens, so I don't think the parents and grandparents thing makes much of a difference.

Expand full comment

Given the level of immune escape, is there any reason to believe that, in countries where Delta is currently dominant, Omicron can substantially reduce the current spread of Delta, or will it just augment the already-high case rates and become the dominant strain in percentage terms? Presumably people can't be co-infected with both strains at the same time, but otherwise is there reason to believe that there's enough short-term protection from one type of infection to substantially reduce the probability of the other? This seems relevant to answering the question of whether the hospitals are likely to get overwhelmed this winter in countries like the UK and US.

Expand full comment

How long do we expect the Omicron crisis to last? If it's doubling every 2.5 days it'll run out of British people to infect by the 8th of January so things will have to have slowed down by then.

Does Omicron seem to progress slower or faster than Covid Classic? You need this figure if you want to turn growth rates into naive herd immunity figures

Expand full comment

Do you think it's likely that, in case Omicron is mild (& _very_ infectious) - it'll mutate into sth not mild? After all, lots of cases = lots of chances of such mutation.

Expand full comment